NASHVILLE, Tenn. — Don't call the Tennessee Titans the NFL's best team just yet. They're happy with being the league's last unbeaten club and grabbing a chokehold on the AFC South away from the Indianapolis Colts.

LenDale White ran for two touchdowns, Chris Hope intercepted Peyton Manning twice and the Titans routed the Colts (3-4), 31-21, last night.

The Titans (7-0) have won an NFL-best 10 straight regular-season games, matching the second-best streak in franchise history. More importantly, Tennessee took control of the AFC South away from the team that has dominated this division in winning the last five titles.

The Titans have won three of four in the series, and linebacker Keith Bulluck said they made a statement with their latest win.

"The Colts were the team to beat, and I think now, the Titans are the team to beat," Bulluck said.

Kerry Collins outmanaged Manning, throwing for 193 yards with no interceptions.

"We're trying to get where they've been," Collins said. "It was a big step for us tonight I think. We obviously got off to a good start, and to get one more against a division opponent is again real big at this time of year."

Jeff Fisher joined Tom Landry and Don Shula as the only NFL coaches to start 7-0 in their 15th season or later. He credited his defense for staying patient against Manning and his team for focusing on the Colts, not its surprising start.

"The season's still early, and there's a lot of games left," Fisher said. "Our focus was on the Colts and trying to prepare ... to try to find a way to beat them."