MADISON, Wis. — After hearing through mutual friends about Richard Davidson's cutting-edge research on the brain and emotions, the Dalai Lama invited him to his home in India in 1992 to pose a question:

Scientists often study depression, anxiety and fear, but why not devote your work to positive human qualities like happiness and compassion?

"I couldn't give him a good answer," recalled Davidson, a University of Wisconsin-Madison neuroscientist.

Since then, Davidson has become a partner in the Dalai Lama's attempts to build a connection between Buddhism and Western science. This weekend, the exiled Tibetan spiritual leader will be present to mark the opening of the Center for Investigating Healthy Minds at the university's Waisman Center, where more than a dozen researchers will study the science behind positive qualities of mind. Davidson noted that the center will have a meditation room side by side with a brain imaging laboratory.

Davidson's research has used brain imaging technology on Buddhist monks and other veteran practitioners of meditation to try to learn how their training affects mental health.

His team's findings suggest that meditation and other "contemplative practices" can improve compassion, empathy, kindness and attention.

"He's made some interesting discoveries about meditation, and I think he is doing very good science," said John Wiley, interim director of the Wisconsin Institutes for Discovery and a former university chancellor.

Initially, "a significant number of his colleagues around the world were suspicious and thought that it wasn't adequately grounded in hard science," Wiley said. "He's proved them wrong."

The Dalai Lama has recently spent more time promoting research into traditional Buddhist meditative practices and urging scientists to help create a more ethical and peaceful world.

Davidson, named one of Time magazine's 100 most influential people in 2006, will appear with the Dalai Lama at scientific events five times this year.

"His relationship with the Dalai Lama lends a great deal of public influence to the hard science that he does," said David Addiss, a former Centers for Disease Control official who now works at the Fetzer Institute, a Michigan nonprofit that gave Davidson a $2.5 million grant.

Yet Davidson's relationship with the Dalai Lama remains controversial. When he invited the Dalai Lama to speak at a 2005 neuroscience conference, dozens of researchers signed a petition in protest. Some of the criticism appeared motivated by Chinese researchers who disagree politically with the Dalai Lama on Tibet. Others called it an inappropriate mix of faith with science.

Davidson, who meditates every morning but does not consider himself a practicing Buddhist, has also been criticized for being too close to someone with an interest in the outcome of his research.

Davidson said the Dalai Lama has said he is prepared to give up any part of Buddhism that is contradicted by scientific fact. "He also is the first one to point out the limitations of meditation and how it's not a cure-all and be-all for everything and has very limited effects on health," Davidson said.

The center plans to begin training local fifth-grade teachers next fall to cultivate skills like patience and relaxation among their students.

"We're really intrigued with his research that shows students can learn how to relax so they can focus more on learning," said Sue Abplanalp, Madison assistant superintendent for elementary schools.